1. Biotechnology Action Program of the European Community Commission (1986-89). (Contract No BAP 0051-GR). Budget: 12.500.000 Grd. Collaboration within the project Bioreactors with the research groups of:

• a. Prof. M.Rossi, Organic & Biological Chemistry lab., Univ. of Napoli, Italy
• b. Dr M.Legoy, Enzymatic Technology lab., Technol.Univ. of Compiegne, France
• c. Prof. K.Schugerl, Inst. of Chemical Technology, Univ. Hannover, Germany.
• d. Prof. A.Ballesteros, Biocatalysis lab. Univ. of Madrid, Spain.

2. Program SCIENCE of the European Community Comission (1988) (Contract No.SC1-0084). Collaboration with the research groups of:

• a. Dr C.Tondre, Organic Physical Chemistry lab, LESOC, Univ. Nancy I, France
• b. Dr J.C.Ravey, Colloidal Physical Chemistry lab, LESOC, Univ. Nancy I, France.

3. Program BRIDGE of the European Community Commission (1991-94): New ways of Biotransformation in non-aqueous systems for the synthesis of pharmaceuticals. Application of supercritical gases, organic solvents, liquid membranes and microemulsions. (Contract N BIOT - CT90 - 0176 (TSTS)). Budget: 900.000 ECU.
Collaboration with the research groups of:

• a. Dr T.Scheper, Inst. of Chemical Technology, Univ. Han­nover, Germany.
• b. Prof. A.Ballesteros, Biocatalysis lab. Univ. of Madrid, Spain.
• c. Dr U.Menge, Enzymatic Technology lab, GBF, Braunschweig, Germany.
• d. Dr D.Combes, Biochemical Engineering lab., INSA Toulouse, France.

4. Program PLATON 1992. "Enzymic studies in microemulsions. Structural aspects''(Contract N 02001910092- 15th Collaboration protocol). Budget: 2.000.000Grd. Collaboration with the research groups:

• a. Prof.M.P.Pileni Structure and Activity on interfaces lab., Univ. Paris VI, France.
• b. Dr C.Petit CEA Saclay, Παρίσι, France.

5. Program PLATON 1993. "Enzymic studies in microemulsions. Structural aspects " (16th Collaboration protocol). Budget: 2.000.000 Grd. Collaboration with the research groups of:

• a. Prof.M.P.Pileni Structure and Activity on interfaces lab., Univ. Paris VI, France.
• b. Dr C.Petit CEA Saclay, Paris, France.

6. Program BIOTECH of the European Union (1994-6) (in collaboration with Prof. Kolisis): "Structure-function lipase relationships in low water media". Budget: 55.000 ECU. Collaboration with the research groups of:

• a. Prof.C.Cambillau, Lab. Cristallographie des Macromolecules Biolog., CNRS, Marseille, France.
• b. Dr. M.R.Egmond, Unilever Research Laboratory, Vlaardingen, The Netherlands.
• c. Prof. S.B.Petersen, SINTEF, MR-Center, Trondheim, Norway.
• d. Prof. M.D.Legoy, Lab. de Genie Proteique, Universite de La Rochelle, France.
• e. Prof.P.Halling, Dept.Bioscience & Biotechnology, Univer.of Strathclyde, Glascow, UK.
• f. Prof. J.M.S.Cabral, Lab. de Engenharia Bioquimica, IST, Lisboa, Portugal.

7. Program ΕΠΕΤ ΙΙ, subprogram 1, ΕΚΒΑΝ-691, (1994-7): "Greek Virgin Olive Oil: Origin Productio Technology & Quality". Budget NHRF: 60.000.000 Grd. Coordinator NHRF: A. Xenakis. Collaboration with the research groups of:

• a. ELAIS SA. Oleaginous Company
• b. Dr.Ε.Chamalidis, Food Department, General State Lab.
• c. Prof. D. Boskou, Food Chem. & Technol. Lab., Univ. of Thessaloniki
• d. Prof. Μ. Komaitis, Dept of Agricultural Industries, Athens Agricultural Univ.
• e. Dr.Α. Koutsaftakis, Inst. of subtropics & olives, Chania, NAGREF.

8. Program ΕΠΕΤ ΙΙ- subprogram 1, ΥΠΕΡ- 55(1996-9) ''Development of a new enzymatic immunoassay for the production of clinical laboratory kits''. Budget: 13.500.000 Grd. Coordinator NHRF: A. Xenakis


9. Program ΕΠΕΤ ΙΙ - subprogram 1, ΠΕΝΕΔ -185 (1996-8) ''Study of the enzymatic activity of hydrolytic enzymes hosted in water in oil microemulsions'' Budget: 10.000.000 Grd. Coordinator NHRF: A. Xenakis

10. Program ΕΠΕΤ ΙΙ - subprogram 2, Action 2.3.Liaison Offices of Universities and Research Centers. (1996-9) ''Development of a Liaison office at the NHRF''. Budget: 72.000.000 Grd. Coordinator NHRF: A. Xenakis

11. Program financed by Pharmathen Ltd. (1997) '' Microemulsions for face cleansers'' Budget: 1.000.000 Grd. Coordinator NHRF: A. Xenakis

12. Program ΕΠΕΤ ΙΙ - Subprogram 2, Action 2.1, ΠΑΒΕ-97ΒΕ93 (1998-2000) ''New technology for transdermal drug delivery. Application of microemulsions and organogels'', Contract with Pharmathen Ltd. ΕΠΕ. Budget: 67.649.087 Grd. (NHRF 14.000.000 Grd.) Coordinator NHRF: A. Xenakis

13. Program ΕΠΕΤ ΙΙ - Action 2.4 R & D Networks, Data Bases, (1998-2000) ''Enzymes in clinical diagnosis and therapy'', Coordinator: T.Sotiroudis. Budget: 26.000.000 Grd Collaboration with National Drug Organization and the Medical school of the Univ.of Athens

14. Program ΕΠΕΤ ΙΙ - Subprogram 2, Action 2.1, ΠΑΒΕ-99ΒΕ5(1999-2001) ''Virgin olive oil: Characterization of the effect of pigments and tocopherols on the oxidative stability and development of a method for the estimation of the oxidative condition'', Contract with: ELAIS SA. Budget: 62.105.000 Grd (NHRF 8.200.000 Grd.) Coordinator NHRF: A. Xenakis

15. Program ΕΠΕΤ ΙΙ - Subprogram 1, Action 2.3, Nutrition Program 97ΔΙΑΤΡΟ-29 (1999-2001) ''Study of the presence and bioavailability of phenolic antioxidants in foods of the Mediterranean diet'' Contract with: Univ. of Thessaloniki Budget: 95.000.000 Grd (NHRF 17.450.000 Grd.) Coordinator NHRF: A. Xenakis
Collaboration with the research groups of:

• a. ELAIS SA. Oleaginous Company
• b. Prof.Α.Kaffatos, Clinic of preventive medicine & nutrition, Medical School, Univ.of Crete
• c. Prof. D. Boskou, Food Chem. & Technol. Lab., Univ. of Thessaloniki
• d. Prof. Ι.Gerothanassis, Org.Chem & Biochem. Lab., Chemistry dept., Univ.of Ioannina

16. Program ΕΠΕΤ ΙΙ - Subprogram 4, Action 4.1, ΠΕΝΕΔ 99ΕΔ74 (1999-2001) ''Biotechnological applications of lipolytic enzymes for the synthesis of high added value products'' Contract with: NTUA. Budget: 52.000.000 Grd (NHRF 15.800.000 Grd) Coordinator NHRF: C.Cazianis Collaboration with the research groups of:

• a. Assoc.Prof.D.Kekos, Biotechnology lab., Chem.Eng. dept. NTUA
• b. Assis.Prof. J.Smonou, Organ.Chem. lab. Chemistry dept., Univ.of Crete.

17. Program ΕΠΕΤ ΙΙ - Subprogram 4, Action 4.1, ΠΕΝΕΔ 99ΕΔ98 (1999-2001)''New materials based on hydrosoluble polymers as carriers of biologically active substances''. Budget: 57.000.000 Grd (NHRF 18.500.000 Grd) Coordinator: A. Xenakis
Collaboration with the research groups of:

• a. Assoc.Prof. G.Staikos, Inst.Chem.Eng/FORTH, Patras
• b. Dr. Α.Malliaris Inst of Physical Chemistry NRC ''Demokritos''

18. Program ΤΕΙ Athens, Cosmetology Dept. School of health professions (1999-2001) ''Lipolytic substances in microemulsions''. Coordinator: Prof.Ε. Protopapa. Budget: 5.000.000 Grd Coordinator NHRF: A. Xenakis

19. Program of Greek-Spanish Collaboration (2000-2001) ''Application of new immobilized enzymic systems for the synthesis of pharmaceutics'' Coordinator NHRF: A. Xenakis. Collaboration with the research group of Prof. J.V. Sinistera Cago, Dept Organic & Pharmaceutical Chemistry, Faculty of Pharmacy Universidad Complutense de Madrid'' Budget: 4.200.000 Grd Coordinator NHRF: A. Xenakis.

20. Program ΕΠΑΝ ΠΑΒΕΤ 2000 00ΒΕ58 (2001-3) ''New systems for delivery of drugs and biologically active substances with repetitive and controlled release'' Contract with: Pharmathen SA. Budget: 83.436.000Grd. (NHRF 3.350.000 Grd.) Coordinator NHRF: A. Xenakis.

21. Program ΕΠΑΝ ''Supporting research groups for exploiting research results. Finding and valorizating results through spin off company creation. PhaseΑ'. Preparation of the investment'' (2002-4) Κωδ. 01 ΠΡΑΞΕ 18. Budget: 44.000,00 €

22. Program IKYDA (2002-5) ''Enzyme immobilization in microemulsion organogels - Study in supercritical fluids''. Collaboration με Prof. Werner Kuntz Institute of Physical and Theoretical Chemistry, Regensburg University, Regensburg, Germany Budget 15.000,00 €

23. Program ''ΣΥΝΕΡΓΑΣΙΑ'' of the Dir.1334/02 - ELAIOURGIKI - ΟΠΕΚΕΠΕ (2003-4) ''Determination of the most significant and usual quality problems encountered in greek olive oils. Evaluation and therapeutic actions'' Budget 23.600,00 €
Collaboration with the research groups of:

• a. ELAIOURGIKI SA.
• b. Assos.Prof.M.Tsimidou, Food Chem. & Technol. Lab., Univ. of Thessaloniki
• c. As.Prof.Ε.Psomiadou, Food Chem lab., Chemistry dept., Univ.of Ioannina

24. Program''Cretan Collaboration'' of the Dir.1334/02 - ΟΠΕΚΕΠΕ - Agr.Unions of Siteia, Peza, Mylopotmos, Mirambello (2004-5) ''Study of the parameters related to the quality of virgin olive oil; effect of the maturity degree on the natural antioxidant content.'' Budget 29.759,52 €

Collaboration with the research group of Prof. Ν.Haniotakis, Chemistry dept., Univ.of Crete