Βιογραφικό Σημείωμα

ΠΛΗΡΕΣ ΒΙΟΓΡΑΦΙΚΟ

Κυριάκος Προυσής
Μεταδιδακτορικός Ερευνητής
Ινστιτούτο Οργανικής & Φαρμακευτικής Χημείας
Εθνικό Ίδρυμα Ερευνών (Ε.Ι.Ε.)

Tel: +302107273890 / Fax: +302107273831
E-mail:kyrprous@eie.gr

ΣΠΟΥΔΕΣ

ΕΡΕΥΝΗΤΙΚΑ ΕΝΔΙΑΦΕΡΟΝΤΑ

• Development of synthetic methodology, organic synthesis (solution and solid phase).
• Synthesis of small heterocyclic molecules.
• Synthesis of natural products and their analogues.
• Microwave-assisted synthesis.
• Synthesis of bioactive molecules.
• Spectroscopic methods of analysis (NMR, FT-IR, GC-MS, LC-MS), chromatographic techniques (HPLC, flash chromatography).

ΔΗΜΟΣΙΕΥΣΕΙΣ

G. Athanasellis, A. Detsi, K. Prousis, O. Igglessi-Markopoulou, J. Markopoulos. "A Novel Access to 2-Amino Furanones via Cyclization of Functionalized γ-Hydroxy-α,β-butenoates Derived from N-Hydroxybenzotriazole Esters of α-Hydroxy Acids." Synthesis 2003, 1, 2015-2022.

A. Detsi, P. Emirtzoglou, K. Prousis, V. Skouridou, O. Igglessi-Markopoulou. "Solid phase synthesis of substituted 2-aminopyrrolin-4-ones via the spontaneous postcleavage cyclization." Synlett 2004, 2, 353-355.

K. C. Prousis, A. Detsi, O. Igglessi-Markopoulou. "A Novel Traceless Solid Phase Approach to Functionalized Tetramic Acids and 2-Amino-4-pyrrolinones."
Synlett 2005, 18, 2763.

S. Kikionis, K. C. Prousis, A. Detsi, O. Igglessi-Markopoulou. "A novel synthetic approach to the thiotetronic ring system, the key intermediate for thiolactomycin analogues." ARKIVOC 2006 (xii) 1-10.

A. Detsi, D. Bouloumbasi, K. C. Prousis, G. Athanasellis, G. Melagraki, A. Afantitis, O. Igglessi-Markopoulou, C. Kontogiorgis, D. Hadjipavlou-Litina. "Design and Synthesis of Novel Quinolinone-3-aminocarboxamides and their α-Lipoic Acid Adducts as Antioxidant and Antiiflammatory Agents." J. Med. Chem. 2007, 50, 2450-2458.

D. Matiadis, K. C. Prousis, O. Igglessi-Markopoulou. "Solid-Phase Synthesis of Optically Active Substituted 2-Aminofuranones Using an Activated Carbonate Linker." Molecules 2009, 14(10), 3914-3921.

K. C. Prousis, J. Markopoulos, V. Mckee, O. Igglessi-Markopoulou "Efficient Efficient construction of functionalized 5-Carboxymethyl Tetramic Acids using N-Ac-L-aspartic Anhydride as Chiral Building Block." Tetrahedron, 2010, 66, 3944-3950.

I. Papanastasiou, K. C. Prousis, K. Georgikopoulou, T. Pavlidis, E. Scoulica, N. Kolocouris, T. Calogeropoulou "Design and synthesis of new adamantyl-substituted antileishmanial ether phospholipids."
Bioorg. Med. Chem.Letters, 2010, 20(18), 5484 - 5487.

Prousis, K. C., Athanasellis G., Stefanou V., Matiadis, D., Kokalari, E., Igglessi-Markopoulou, O., Mc Kee, V., Markopoulos, J. "Synthesis and crystal structure characterization of zinc (II) tetronic acid complexes"
Bioinorganic Chemistry and Applications, accepted, (in Press), Volume 2010,
Article ID 651652, doi:10.1155/2010/651652