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Curriculum Vitae

Dr. Fotini-Chryssanthi J. Andreadaki
Post-doctoral Research Fellow

National Hellenic Research Foundation
Institute of Biology, Medicinal Chemistry and Biotechnology
Division of Organic & Medicinal Chemistry (OMC)
48, Vassileos Constantinou Avenue,
GR-11635 Athens Greece
Tel. / Fax : +30 210 7273874 / + 30 210 7273831
E-mail: fandread

Education
1995 :   PhD in Biochemistry, University of Athens
1987 :   B.Sc.  in Biology, University of Athens

Employment

2010-present Post-doctoral Fellow with Dr. E. Chrysina, National Hellenic Research Foundation (Athens)
2003-2010  Post-doctoral Fellow with Dr. I.D. Kostas, National Hellenic Research Foundation (Athens)
2000-2001  Post-doctoral Fellow with Prof. K. Iatrou, National Center for Scientific Research ''Democritos'' (Athens)
4/1998-7/1998 Post-doctoral Fellow with Prof. M. Typas University of Athens (Athens)
1997-3/1998   Post-doctoral Fellow with Prof. F. Wunderlich, Heinrich Heine Universität (Düsseldorf)
1996-1997  Post-doctoral Fellow with Prof. M. Typas, University of Athens (Athens)
1995-1996 Post-doctoral Fellow with Prof. F. Wunderlch, Heinrich Heine Universität (Düsseldorf)  
1988-1992 Doctoral fellow with Dr. F.Kolisis National Hellenic Research Foundation (Athens)
1994-1995 Post-doctoral Fellow with Prof. Dr. P.H.Pouwels, Universiteit van Amsterdam (Amsterdam)

Research Interests

  • Sialic acid metabolism in Lactic acid bacteria.
  • Studies in S-layer protein in L. acidophilus strain used as a model of live vaccine.
  • Genetic engineering studies of sugar metabolism in Lactic acid Bacteria
  • Construction of  new recombinant Baculoviruses to be used as improved biological insecticides
  • Protein expression studies in Heterologous Expression Systems
  • Toxicity studies of new synthesized drugs in cancer cell lines
  • Dendrimer mediated in DNA transfer into the cells
  • Structural studies of glycogen phosphorylase isoenzymes in complex with potential hypoglycaemic agents for the treatment of type 2 diabetes disease with X-ray protein crystallography
  • Development of new biochemical assays for in vitro assessment/screening of newly synthesized compounds for further studies with the method of structure-based drug design

Selected Publications

  • Andreadaki F.J., Kolisis F.N., Sakellaris G., Evangelopoulos A.E., Biotechn. Appl. Biochem. 1990, 12, 653-660
  • H.J. Boot, C.P.A.M. Kolen, F.J. Andreadaki, P.J. Leer, P.H. Pouwels, J. Bacteriol. 1996, 178 (18), 5388-5394
  • D. Kovala-Demertzi, P.N. Yadav, M.A. Demertzis, J.P. Jasinski, F.J. Andreadaki, I.D. Kostas, Tetrahedron Lett. 2004, 45, 2923-2926
  • I.D. Kostas, B.R. Steele, F.J. Andreadaki, V.A. Potapov, Inorg. Chim. Acta 2004, 357, 2850-2854
  • I.D. Kostas, F.J. Andreadaki, D. Kovala-Demertzi, C. Prentjas, M.A. Demertzis, Tetrahedron Lett. 2005, 46, 1967-1970
  • E.I. Tolis, K.A. Vallianatou, F.J. Andreadaki, I.D. Kostas, Appl. Organomet. Chem. 2006, 20, 335-337
  • I.D. Kostas, G.A. Heropoulos, D. Kovala-Demertzi, P.N. Yadav, J.P. Jasinski,  M.A. Demertzis, F.J. Andreadaki, G. Vo-Thanh, A. Petit, A. Loupy, Tetrahedron Lett. 2006, 47, 4403-4407
  • D. Kovala-Demertzi, N. Kourkoumelis, K. Derlat, J. Michalak, F.J. Andreadaki, I.D. Kostas Inorg. Chim. Acta 2008, 361, 1562-1565
  • I.D. Kostas, F.J. Andreadaki, E.A. Medlycott, G.S. Hanan, E.  Monflier, Tetrahedron Lett. 2009, 50 (16), 1851-1854
  • F.J. Andreadaki, I.D. Kostas, B.R. Steele, V. Zoumpourlis. "Antiproliferative activity of palladium complexes with chalcogen-containing Schiff-base ligands" manuscript in preparation
 
   

Last Update: 02.07.2012
İ National Hellenic Research Foundation (NHRF), 48 Vassileos Constantinou Ave., 11635 Athens, Greece, Tel. +302107273700, Fax. +302107246618