Curriculum Vitae

Constantinos Baskakis
Postdoctoral fellow in National Hellenic Research Foundation
Institute of Biology, Medicinal Chemistry and Biotechnology
Division of Organic & Medicinal Chemistry (OMC)
Address: National Hellenic Research Foundation (NHRF),
48 Vassileos Constantinou Ave, 11635 Athens.
Tel: +302107273890 / Fax: +302107273831
E-mail:kbaska

Education
2005 -  2009, PhD in Chemistry, University of Athens, Greece.
2003 -  2005, M. Sc. in Chemistry, University of Athens, Greece.
1999 -  2003, B. Sc. in Chemistry, University of Crete,Greece.

Research Interest

• Design and synthesis of chiral organocatalysts for practical asymmetric synthesis.
• Synthesis of medicinal and biological active molecules for selective inhibition.
• Fluorine chemistry.

List of Publications

• ''Dye-sensitized intrazeolite photooxygenation of 4-substituted cyclohexenes. Remote substituent effects in regioselectivity and diastereoselectivity'' Stratakis, M.; Sofikiti, N.; Baskakis, C.; Raptis, C. Tetrahedron Lett., 2004, 45, 5433-5436.
• ''Intrazeolite photooxygenation of chiral alkenes. Control of facial selectivity by confinement and cation-π interactions'' Stratakis, M.; Raptis, C.; Sofikiti, N.; Tsangarakis, C.; Kosmas, G.; Zaravinos, I.-P.; Kalaitzakis, D.; Stavroulakis, D.; Baskakis, C.; Stathoulopoulou, A. Tetrahedron, 2006, 62, 10623-10632.
• ''Intracellular phospholipase A2 group IVA and group VIA play important roles in Wallerian degeneration and axon regeneration after peripheral nerve injury'' Lopez-Vales, R.; Navarro, X.; Shimizu, T.; Baskakis, C.; Kokotos, G.; Constantinou-Kokotou, V.; Stephens, D.; Dennis, E. A.; David, S. Brain, 2008, 131, 2620-2631.
• ''Synthesis of Medicinally Interesting Polyfluoro Ketones via Perfluoroalkyl Lithium Reagents'' Kokotos, C.; Baskakis, C.; Kokotos, G. J. Org. Chem., 2008, 73, 8623-8626.
• ''Synthesis of Polyfluoro Ketones for Selective Inhibition of Human Phospholipase A2 Enzymes'' Baskakis, C.; Magrioti, V.; Cotton, N.; Stephens, D.; Constantinou-Kokotou, V.; Dennis, E. A.; Kokotos, G. J. Med. Chem., 2008, 51, 8027-8037.
• ''Differing roles for members of the phospholipase A2 superfamily in experimental autoimmune encephalomyelitis'' Kalyvas, A.; Baskakis, C.; Magrioti, V.; Constantinou-Kokotou, V.; Stephens, D.; Lopez-Vales, R.; Lu, J.-Q.; Yong, V. W.; Dennis, E. A., Kokotos, G.; David, S. Brain, 2009, 132, 1221-1235.
• ''Potent and Selective Fluoroketone Inhibitors of Group VIA Calcium-Independent Phospholipase A2'' Kokotos, G.; Hsu, Y. H.; Burke, J. E.; Baskakis, C.; Kokotos, C. G.; Magrioti, V.; Dennis, E. A. J. Med. Chem., 2010, 53, 3602-3610.

Patent
WO 2008122119 (A1), 16-10-2008, ''Perfluoroketone compounds and uses thereof''. David, Samuel; Kalyvas, Athena; Lopez-Vales, Ruben; Kokotos, George; Constantinou-Kokotou, Violetta; Baskakis, Constantinos; Kokotos, Christoforos G.; Dennis, Edward A.; Stephens, Daren.