Curriculum Vitae

Alexandra Tsatsaroni                                                                                                 
Chemist

National Hellenic Research Foundation (NHRF),
Institute of Biology, Medicinal Chemistry and Biotechnology
Division of Organic & Medicinal Chemistry (OMC)
Vassileos Constantinou Ave  48th,
116 35 Athens

Tel: +30 2107273890
E-mail: atsatsaroni@gmail.com

EDUCATION

2008 - 2010:

MSc fellow at the Institute of Organic and Pharmaceutical Chemistry, National Hellenic Research Foundation in collaboration with the Pharmacy Department.of the National and Kapodistrian University of Athens,
''Design and synthesis of benzopyran analogues bearing heterocyclic five-membered rings, such as 1,2,3-triazole and isoxazole synthesized using ''click'' reactions and evaluation of their activity against glutamate neurotoxicity. Research also involves solid phase synthesis of 2-substituted chromans.''

2003 - 2007:
• Bachelor degree in Chemistry with grade 8.04
University of Patras, Faculty of Sciences, Chemistry Department.
Undergraduate thesis: ''Synthesis of butyl imidazole and histamine analogues with potential antihypertensive activity''. Laboratory of Organic Chemistry, University of Patras. (October 2006 - May 2007)

Languages

Greek : Native speaker
English: Fluently
French: Working knowledge
Spanish: Good knowledge

Conferences - Presentations

• Maria Koufaki, Christina Kiziridi, Xanthippi Alexi, Helene Guerrand, Alexandra Tsatsaroni, Michael N. Alexis. Design and synthesis of novel neuroprotective 1,2-dithiolane/chroman hybrids.16th European Symposium on Organic Chemistry, Prague,  Czech Republic 12-16 July 2009.
• Maria Koufaki, Elissavet Theodorou, Helene Guerrand, Xanthippi Alexi, Alexandra Tsatsaroni, Michael N.Alexis. Design and synthesis of new neuroprotective chroman analogues bearing catechol substituants.  11th Conference in Advanced Medicinal Chemistry, Thessaloniki, Greece, May 23-24 2009.
• Alexandra Tsatsaroni, Maria Koufaki, Xanthippi Alexi, Michael N.Alexis Design and synthesis of novel neuroprotective chroman analogues.14th Hellenic Symposium on Medicinal Chemistry, Thessaloniki, Greece, April 23-25, 2010.
• Alexandra Tsatsaroni, Maria Koufaki, Xanthippi Alexi, Michael N.Alexis Design and synthesis of novel neuroprotective chroman analogues.  3d European Workshop in Drug synthesis, Certosa di Pontignano, Siena-Italy, May 23-27, 2010

Computer skills

• Excellent knowledge of MS Windows, MS Office
• q-Basic
• OriginLab Origin, Chembridgesoft Chembiooffice, Hg (Mercury), MestRec, Hyperchem, SciFinder, Beilstein

Laboratory techniques

Analytical techniques: column chromatography, HPLC, NMR, ATR-IR, GC, GC-MS, UV.

My research experience includes:

• Synthesis of sartan derivatives withpotential antihypertensive activity, mimics of angiotensine (AGII)
• Synthesis of benzopyran analogues bearing heterocyclic five-membered rings with potential neuroprotective and antioxidant activity.
• Synthesis using microwaves, ultrasound as well as solid phase synthesis.
• Performing low temperature reactions (NESLAB cryocool) under inert atmosphere or with the exclusion of oxygen.
• Performing reactions in a small scale (μM)
• Molecular modelling techniques
• Purification of organic compounds using a variety of chromatographic techniques including:
• flash column chromatography
• gravity column chromatography
• preparative thin-layer chromatography
• High Performance Liquid Chromatography (HPLC)
• Characterization of organic compounds using IR spectroscpy, NMR spectroscopy (1D and 2D) and mass spectrometry
• Experienced in the use of the following scientific equipment:
• Varian NMR (V300 and V600 MHz)
• MSQ ESI/APCI-MS of Finnigan Series
• HPLC of Agilent Series and Thermo Scientific HPLC Spectra System
• Thermo Scientific Fleet LC-MS
• Syncore Buchi Parallel synthesis Apparatus
• CEM Discover Microwave Apparatus
• Tensor 27 Bruker FT-IR equipped with an ATR-unit

Member of scientific communities

• Member of the Association of Greek Chemists