Organic and Organometallic Chemistry Group
Tel.: +30 210 7273874
Fax: +30 210 7273831 E-mail: carol
Research Interests
My current research focuses on the synthesis of novel bioactive molecules and new organometallic functional materials:
Stilbene derivatives with neuroprotecting activity
Ferrocene-based near-infrared dyes
We have also initiated projects in the area of dendrimer chemistry, including the synthesis and study of organometallic dendrimeric near-infrared dyes with applications for the photodynamic therapy of cancer and in the design and synthesis of dendritic compounds as neuroprotective agents.
Publications
'Microwave assisted solid additive effects in simple dry chlorination reactions with n-chlorosuccinimide'
M. Bucos, C. Villalonga-Barber, M. Micha-Screttas, B. R. Steele, C. G. Constantinos, G. A. Heropoulos, Tetrahedron, 2010, 66, 2061.
'Dendrimers as biopharmaceuticals: Synthesis and properties'
C. Villalonga-Barber, M. Micha-Screttas, B. R. Steele, A. Georgopoulos, C. Demetzos, Curr. Top. Med. Chem., 2008, 8, 1294-1309.
'Engineered chmieric enzymes as tools for drug discovery: Generating reliable bacterial screens for the detection, discovery, and assessment of estrogen receptor modulators'
G. Skretas, A. KMeligova, C. Villalonga-Barber C, D. J. Mitsiou, M. N. Alexis, M. Micha-Screttas, B. R. Steele, C. G. Screttas, D. W. Wood, J. Am. Chem. Soc., 2007, 129, 8443-8457.
'New stable, isolable triaylmethyl based dyes absorbing in the near IR'
C. Villalonga-Barber, B. R. Steele, V. Kovac, M. Micha-Screttas and C. G. Screttas, J. Organomet. Chem., 2006, 691, 2785-2792.
'Selective catalytic carbanionic ethylation of methylphenols. Influence of catalyst and substitution pattern'
B. R. Steele, C. Villalonga-Barber, M. Micha-Screttas and C. G. Screttas, Tetrahedron, 2006, 47, 2093-2097.
'Selectivity in the Cycloadditions of Carbonyl Ylides with Glyoxylates: an approach to the Zaragozic Acids-Squalestatins'
D. M. Hodgson, J. M. Bailey, C. Villalonga-Barber, M. G. B. Drew and T. Harrison, J. Chem. Soc., Perkin Trans. 1, 2000, 3432-3443.
'Studies towards a Stereocontrolled Synthesis of the Tricarboxylate Core of the Zaragozic Acids-Squalestatins by a Cycloaddition-Rearrangement Strategy' D. M. Hodgson and C. Villalonga-Barber, Tetrahedron Lett., 2000, 41, 5597-5609.
'Synthesis and Diels-Alder Reactivity of Chiral 2-(Alk-1-enyl)-1,3,2-diazaphospholidine 2-oxides' P. B. Wyatt, C. Villalonga-Barber and M. Motevalli, Tetrahedron Lett., 1999, 40, 149-152.
Patents
'New substituted stilbenoid derivtives with neuroprotective activity', M. Micha-Screttas, C. Villalonga-Barber, B. R. Steele, M. N. Alexis. Patent number: 1005435.