Βιογραφικό Σημείωμα

Full list of publications

Dr. Spyros E. Zographos
Associate Researcher
Institute for Biology, Pharmaceutical Chemistry & Biotechnology
Department for Organic & Medicinal Chemistry (OMC)
E-mail: sez

Academic formation
1992         Diploma in Chemistry, Dept. of Chemistry, University of Athens
1997           PhD in Chemistry, Dept. of Chemistry, University of Athens

Fellowships

1992-1997:         PhD fellowship, National Hellenic Research    
2001-2004:         Marie Curie Post Doctoral fellowship 
2004-2005:      Marie Curie Post Doctoral fellowship

Professional profile

1999-2000        Post-doctoral Research Fellow, Institute of Biological Research and
                       Biotechnology (IBRB), NHRF
2000-2001        Visiting Lecturer, Department of Chemistry, University of Cyprus
2001-2004        Post-doctoral Research Fellow, Department of Biological Sciences, University                        of Cyprus
2004-2006          Post-doctoral Research Fellow, Institute of Organic and Pharmaceutical                        Chemistry (IOPC), NHRF
2006-2009          Research Assistant, IOPC, NHRF

Research interests

His main fields of specialization are biochemistry, molecular biology, enzyme kinetics, X-ray protein crystallography and structure-based drug design. His major research interests are focused on functional and structural studies of enzymes involved in type 2 diabetes mellitus (glycogen phosphorylase, phosphorylase kinase, glucokinase and phosphoenolpyruvate carboxykinase), nucleotide homeostasis (Adenylate kinase 6) and transmission of malaria (Odorant Binding Proteins from mosquito Anopheles gambiae).

Synopsis of scientific achievements

His scientific achievements are presented in 50 peer-reviewed articles (h-index: 21, i10-index: 35 Times Cited: total 1,237, without self-citations: 1.051),  3 reviews, 3 chapters in books, 40 oral /poster presentations in conferences and 21 short communications. Five of his articles were presented in the cover of the respective issues of scientific journals  Proteins, Acta Crystallographica F, Bioorganic & Medicinal Chemistry, European Journal of Biochemistry and Protein Science.
Dr. Zographos is registered user (since 1992) of the European Synchrotron Radiation Sources, Daresbury Laboratory, Daresbury, UK, Sinchrotrone Trieste, Trieste, Italy, EMBL, Hamburg-Outstation, DESY and Lund-MaxLab, and has carried out 48 visits for X-ray crystallographic data collection through grant applications.

Teaching experience

Dr. Zographos has significant teaching experience: As a visiting lecturer at the Chemistry Department of University of Cyprus, he taught Medicinal Chemistry, Biochemistry, X-ray Protein Crystallography (undergraduate courses) and Enzymology-Structural Biology as part of a postgraduate course. Furthermore, he has been co-organizer and/or tutor for eight workshops and two international scientific symposiums on structure-based drug design. He has supervised 4 MSc and 2 final year research projects and currently is supervising 1 PhD Thesis and 1 MSc research project.

Research funding

His current research activities are supported by the EU-FP7 competitive programs

''ARCADE: Advancement of Research Capability for the Development of New Functional Compounds'' FP7-REGPOT-2009-1. (2010-2012). http://www.arcade-iopc.eu/default.aspx., Budget for SBCG 205.000 €,

''EUROSTRUCT: European consolidation and promotion of research capacity in the area of structure based drug discovery''. FP7-REGPOT-2008-1, (GA-230146), (2009-2011). http://athena.eie.gr/eurostruct/index.html, Budget for SBCG 1.000.000 €

''ENAROMATIC: European Network for Advanced Research on Olfaction for Malaria Transmitting Insect Control.'' FP7-HEALTH-2007-2.3.2-9, (GA-222927), (2009-2012). Budget for SBCG 280.000 €.
For more information about ENAROMaTIC see:
http://athena.eie.gr/enaromatic.html
http://www.enaromatic.org/
http://technologein.pathfinder.gr/enaromatic video in Greek
http://www.who.int/mediacentre/factsheets/fs094/en/index.html

Collaborations

ENAROMaTIC consortium which aims to reduce malaria transmission rates consists of ten institutions from 7 EU countries, 1 from USA and 1 from Nigeria. The current list of Dr. Zographos' collaborators also includes research teams from Japan and China.

Other scientific activities