OOMCG Publications and Patents

2005

C. Arbez-Gindre, B.R. Steele, G.A. Heropoulos, C.G. Screttas, J.-E. Communal, W.J. Blau, I. Ledoux-Rak
''A facile organolithium route to ferrocene-based triarylmethyl dyes with substantial near IR and NLO properties''
J. Organomet. Chem. 2005, 690, 1620-1626

G.A. Heropoulos, S. Georgakopoulos, B.R. Steele
''High intensity ultrasound assisted reduction of sterically demanding nitroaromatics''
Tetrahedron Lett. 2005, 46,  2469-2473 

C.G. Screttas, G.A. Heropoulos, M. Micha-Screttas, B.R. Steele
''Medium-dependent lithiated side products in the reductive lithiation of allylic phenyl thioethers. Diethyl ether versus tetrahydrofuran''
Tetrahedron Lett. 2005, 46, 4357-4360

S. Mastronicolis, N. Arvanitis, A. Karaliota, C. Litos, G. Stavroulakis, H. Moustaka, A. Tsakirakis and G. A. Heropoulos
''Cold dependence of fatty acid profile of different lipid structures of Listeria monocytogenes''
Food Microbiol. 2005, 22 (2-3), 213-219

I.D. Kostas, K.A. Vallianatou, J. Holz, A. Borner
''Rhodium complexes with a new chiral nitrogen-containing BINOL-based diphosphite or phosphonite ligand: synthesis and application to hydroformylation of styrene and/or hydrogenation of prochiral olefins''
Appl. Organomet. Chem. 2005, 19(10), 1090-1095

N.V. Dubrovina, V.I. Tararov, A. Monsees, A. Spannenberg, I.D. Kostas, A. Borner
''New chiral 1,3-diphosphine ligands for Rh-catalyzed enantioselective hydrogenation: a search for electronic effects''
Tetrahedron: Asymmetry 2005, 16(22), 3640-3649

I.D. Kostas, F.J. Andreadaki, D. Kovala-Demertzi, C. Prentjas, M.A. Demertzis
''Suzuki-Miyaura cross-coupling reaction of aryl bromides and chlorides with phenylboronic acid under aerobic conditions catalyzed by palladium complexes with thiosemicarbazone ligands''
Tetrahedron Lett. 2005, 46(12), 1967-1970

S.V. Amosova, N.A. Makhaeva, A.V. Martynov, V.A. Potapov, B.R. Steele, I.D. Kostas
''Terminal organochalcogenoethyl- and -propylamines and their Schiff base derivatives''
Synthesis 2005, (10), 1641-1648

N.G. Oikonomakos, M.N. Kosmopoulou, E.D. Chrysina, D.D. Leonidas, I.D. Kostas, K.U. Wendt, T. Klabunde, E. Defossa
''Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs''
Protein Sci. 2005, 14(7), 1760-1771

2006

B.R. Steele C. Villalonga-Barber, M. Micha-Screttas, C.G. Screttas
''Selective catalytic carbanionic ethylation of methylphenols. Influence of catalyst and substitution pattern''
Tetrahedron Lett. 2006, 47, 2093-2097.

C. Villalonga-Barber, B.R. Steele V. Kovac, M. Micha-Screttas, C.G. Screttas
''New stable, isolable triarylmethyl based dyes absorbing in the near infrared''
J. Organomet. Chem. 2006, 691, 2785-2792.

G. Cravotto, L. Boffa, M. Bia, W. Bonrath, M. Curini and G. A. Heropoulos
''An Easy Access to Aromatic Azo Compounds under Ultrasound/Microwave Irradiation''
Syn Lett, 2605-2609, 2006.

S. K, Mastronicolis A. Boura, A. Karaliota, P. Magiatis, N. Arvanitis, C. Litos, A. Tsakirakis, P. Paraskevas, H. Moustaka and G. A. Heropoulos
''Effect of cold temperature on the composition of different lipid classes of the foodborne pathogen Listeria monocytogenes: Focus on neutral lipids''
Food Microbiol. 23,  184–194, 2006.

K.A. Vallianatou, I.D. Kostas, J. Holz, A. Borner
''Me-AnilaPhos: A new chiral phosphine–phosphoramidite ligand for a highly efficient Rh-catalyzed asymmetric olefin hydrogenation''
Tetrahedron Lett. 2006, 47(45), 7947-7950
Selected comments: (a) ''excellent catalyst'' (a critical review: L. Eberhardt, D. Armspach, J. Harrowfield, D. Matt Chem. Soc. Rev. 2008, 37, 839); (b) ''highly versatile ligand class'' (ALDRICH: D. Amoroso et al. Aldrichimica Acta, 2008, 41, 20).

E.I. Tolis, K.A. Vallianatou, F.J. Andreadaki, I.D. Kostas
''A new rhodium complex with a nitrogen-containing bis(phosphine oxide) ligand as an efficient catalyst for the hydroformylation of styrene''
Appl. Organomet. Chem. 2006, 20(5), 335-337

I.D. Kostas, G.A. Heropoulos, D. Kovala-Demertzi, P.N. Yadav, J.P. Jasinski, M.A. Demertzis, F.J. Andreadaki, G. Vo-Thanh, A. Petit, A. Loupy
''Microwave-promoted Suzuki-Miyaura cross-coupling of aryl halides with phenylboronic acid under aerobic conditions catalyzed by a new palladium complex with a thiosemicarbazone ligand''
Tetrahedron Lett. 2006, 47(26), 4403-4407

I.D. Kostas, B.R. Steele, A. Terzis, S.V. Amosova, A.V. Martynov, N.A. Makhaeva
''New Palladium Complexes with S- or Se-Containing Schiff-Base Ligands as Efficient Catalysts for the Suzuki-Miyaura Cross-Coupling Reaction of Aryl Bromides with Phenylboronic Acid under Aerobic Conditions''
Eur. J. Inorg. Chem. 2006, (13), 2642-2646

N.G. Oikonomakos, M.N. Kosmopoulou, D.D. Leonidas, E.D. Chrysina, C. Tiraidis, N. Bischler, K.E. Tsitsanou, S.E. Zographos, I.D. Kostas, G. Eisenbrand
''Indirubin and indigo analogues as potential inhibitors of glycogenolysis: structural basis of glycogen phosphorylase inhibition''. In Indirubin, the red shape of indigo, L. Meijer, N. Guyard, L.A. Skaltsounis, G. Eisenbrand (eds.).
Editions ''Life in Progress'', Roscoff, 2006, Chapter 18, 177-189.

2007

G.A. Heropoulos, G. Cravotto, C.G. Screttas, B.R. Steele
''Contrasting chemoselectivities in the ultrasound and microwave assisted bromination reactions of substituted alkylaromatics with N-bromosuccinimide''
Tetrahedron Lett. 2007, 48, 3247-3250.

G.C. Papavassiliou, G.C. Anyfantis, B.R. Steele, A.Terzis, C.P. Raptopoulou, G. Tatakis, G. Chaidogiannos, N. Glezos, Y. Weng, H. Yoshino, K. Murata
''Some new nickel 1,2-dichalcogenolene complexes as single-component semiconductors''
Z. Naturforsch. B 2007, 62b, 679-684

B.R. Steele, G.A. Heropoulos, C.G. Screttas
''Metal chloride reductions with aromatic radical anions. The magnesium chloride catalysed cleavage of tetrahydrofuran by sodium naphthalene radical anion''
Collect. Czech. Chem. Commun. 2007, 72, 589-598.

B.R. Steele, S. Georgakopoulos, M. Micha-Screttas, C.G. Screttas
''Synthesis of new sterically hindered anilines''
Eur. J. Org. Chem. 2007, 3091-3094

G. Skretas, A. Meligova, C. Villalonga-Barber, D.J. Mitsiou, M.N. Alexis, M. Micha-Screttas, B.R. Steele, C.G. Screttas, D.W. Wood
''Engineered chimeric enzymes as tools for drug discovery: Generating reliable bacterial screens for the detection, discovery and assessment of estrogen receptor modulators''
J. Am. Chem. Soc. 2007, 129, 8443 - 8457.

G. Pagona, A.S.D. Sandanayaka, A. Maigne, J. Fan, G.C. Papavassiliou, I.D. Petsalakis, B.R. Steele, M. Yudasaka, S. Iijima, N. Tagmatarchis, O.Ito
''Photo-induced electron-transfer on aqueous carbon nanohorn-pyrene-tetrathiafulvalene architectures''
Chem. Eur. J. 2007, 13, 7600-7607.

I.D. Kostas, A.G. Coutsolelos, G. Charalambidis, A. Skondra
''The first use of porphyrins as catalysts in cross-coupling reactions: a water-soluble palladium complex with a porphyrin ligand as an efficient catalyst precursor or the Suzuki–Miyaura reaction in aqueous media under aerobic conditions''
Tetrahedron Lett. 2007, 48(38), 6688-6691

K.A. Chatziapostolou, K.A. Vallianatou, A. Grigoropoulos, C.P. Raptopoulou, A. Terzis, I.D. Kostas, P. Kyritsis, G. Pneumatikakis
''Synthesis and characterization of new RhI complexes bearing CO, PPh3 and chelating P,O- or Se,Se-ligands. Application to hydroformylation of styrene''
J. Organomet. Chem. 2007, 692(19), 4129-4138

Patent

2007

M. Micha-Screttas, C. Villalonga Barber, B.R. Steele, M.N. Alexis, GR 1005435
«Νέα  υποκατεστημένα στιλβενοειδή παράγωγα με νευροπροστατευτική δράση»
[''New substituted stilbenoid derivatives with neuroprotective activity'']

2008

I.D. Kostas
''Other P/N-Ligands'' (Chiral Bidentate Monophosphorus Ligands: Hybrid Monophosphorus Ligands – Bidentate P/NR2 Ligands – Other P/N-Ligands). In Phosphorus Ligands in Asymmetric Catalysis – Synthesis and Applications, A. Borner (Ed.), Wiley-VCH, Weinheim, 2008, vol. 2, part IV, chapter 1.2, pp. 596-632.
Invited book chapter

I.D. Kostas
''Recent Advances on P,N-Containing Ligands for Transition-Metal Homogeneous Catalysis''
Curr. Org. Synth. 2008, 5(3), 227-249

I.D. Kostas, K.A. Vallianatou, J. Holz, A. Borner
''A new easily accessible chiral phosphite-phosphoramidite ligand based on 2-anilinoethanol and R-BINOL moieties for Rh-catalyzed asymmetric olefin hydrogenation''
Tetrahedron Lett. 2008, 49(2), 331-334

D. Kovala-Demertzi, N. Kourkoumelis, K. Derlat, J. Michalak, F.J. Andreadaki, I.D. Kostas
''Thiosemicarbazone-derivatised palladium nanoparticles as efficient catalyst for the Suzuki-Miyaura cross-coupling of aryl bromides with phenylboronic acid''
Inorg. Chim. Acta 2008, 361(5), 1562-1565

S.V. Amosova, V.N. Elokhina, A.S. Nakhmanovich, L.I. Larina, A.V. Martynov, B.R. Steele; V.A. Potapov
''Reactions of selenourea with benzoyl- and 2-thienoylbromo-acetylenes: synthesis of 1,3-diselenetanes and 1,4-diselenafulvenes''
Tetrahedron Lett. 2008, 49, 974-976.

F. Wiesbrock, C. Patteux, T.K. Olszewski, A. Blanrue, G.A. Heropoulos, B.R. Steele, M. Micha-Screttas and T. Calogeropoulou
''Solution-phase synthesis and scale-up of 1st generation tetraester-dendritic branches involving microwave and/or ultrasonic irradiation''
Eur. J. Org. Chem. 2008, 4344-4349.

C. Villalonga-Barber, M. Micha-Screttas, B.R. Steele, A. Georgopoulos, C. Demetzos
''Dendrimers as biopharmaceuticals: Synthesis and properties''
Curr. Top. Med. Chem. 2008, 8, 1294-1309.

S. K. Mastronicolis, N. Arvanitis, A. Karaliota, P. Magiatis, G. A. Heropoulos, C. Litos, H. Moustaka, A. Tsakirakis, E. Paramera, and P. Papastavrou.
''Coordinated Regulation of Cold-Induced Changes in Fatty Acids with Cardiolipin and Phosphatidylglycerol Composition among Phospholipid Species for the Food Pathogen Listeria monocytogenes''
Appl. Envir. Microbiol. 74, 4543-4549, 2008.

Maria Micha-Screttas, and Helmut Ringsdorf
''Polymer Science and Polymer Therapeutics: Macromolecules, Dendrimers and Nanomedicine.'' 
Cur. Top., Med. Chem, 2008, 8, 14,  1294-1309,  

2009

I.D. Kostas, F.J. Andreadaki, E.A. Medlycott, G.S. Hanan, E. Monflier
''Synthesis of a halo-methylphenylene periphery-functionalized triazine-based dendritic molecule with a 3,3/-dimethyl-biphenyl linker using tris(halo-methylphenylene)triazines as building blocks''
Tetrahedron Lett. 2009, 50(16), 1851-1854

A.-C. Tenchiu (Deleanu), I.D. Kostas, D. Kovala-Demertzi, A. Terzis
''Synthesis and characterization of new aromatic aldehyde/ketone 4-(β-D-glucopyranosyl)thiosemicarbazones''
Carbohydr. Res. 2009, 344(11), 1352-1364

S. Aime, E. Gianolio, F. Arena, A. Barge, K. Martina, G. A. Heropoulos, G. Cravotto
''New cyclodextrin dimers and trimers capable of forming supramolecular adducts with shape-specific ligands''.
Org. Biomol. Chem., 7, (2), 370-379, 2009

2010

M. Bucos, C. Villalonga-Barber, M. Micha-Screttas, B.R. Steele, C.G. Screttas, G.A. Heropoulos
''Microwave assisted solid additive effects in simple dry chlorination reactions with N-chlorosuccinimide''
Tetrahedron 2010, 66, 2061-2065

K. Gardikis, S. Hatziantoniou, M. Bucos, D. Fessas, M. Signorelli, T. Felekis, M. Zervou, C.G. Screttas, B.R. Steele, M. Ionov, M. Micha-Screttas, B. Klajnert, M. Bryszewska, C. Demetzos
''New drug delivery nanosystem combining liposomal and dendrimeric technology (liposomal locked-in dendrimers) for cancer therapy''
J. Pharm. Sci. 2010, 99, 3561-3571.

D. M. Hodgson, C. Villalonga-Barber, J. M. Goodman, S. C.  Pellegrinet, S. C.
''Synthetic and computational studies on the tricarboxylate core of 6,7-dideoxysqualestatin H5 involving a carbonyl ylide cycloaddition-rearrangement''
Org. & Biom. Chem. 2010, 8, 3975-3984

K. Gardikis; S. Hatziantoniou; M. Signorelli; M. Pusceddu; M. Micha-Screttas; A. Schiraldi; C. Demetzos; D. Fessas,
''Thermodynamic and structural characterization of Liposomal-Locked in-Dendrimers as  drug carriers''
Colloids and Surfaces B: Biointerfaces, 2010, Ref. No.: COLSUB-D-10-00352R1

Konstantinos Gardikis,  Chrisiida Tsimplouli,  Konstantinos Dimas,  Maria Micha-Screttas , Costas Demetzos
''New Chimeric  Advanced Drug Delivery Nanosystems (Chi-aDDnSs) as Doxorubicin’s carriers''
Int. J. of Pharmac, .2010, accepted

K.-M. Alexacou, A.-C. Tenchiu (Deleanu), E.D. Chrysina, M.-D. Charavgi, I.D. Kostas, S.E. Zographos, N.G. Oikonomakos, D.D. Leonidas
''The binding of β-d-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitors''
Bioorg.Med.Chem. 2010,doi: 10.1016/j.bmc.2010.09.039