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CLOSEPostdoctoral Fellowship under the Marie Skłodowska-Curie Actions for the project CryoLipNano awarded to Dr. Panagiota Papadopoulou
Dr. Panagiota Papadopoulou has been awarded a Marie Skłodowska-Curie Postdoctoral Fellowship (HORIZON-MSCA-2024-PF-01-01) for the project CryoLipNano, with a total budget of €197,263.68, which will be implemented at the Institute of Chemical Biology (ICB) of NHRF.
The project focuses on investigating the ultrastructure and intracellular trafficking of RNA lipid nanoparticles (LNPs) using advanced cryo-electron microscopy, imaging techniques, and proteomics. LNPs currently represent the most advanced and clinically approved platform for RNA delivery, yet only a small fraction successfully releases RNA into the cell cytoplasm.
CryoLipNano aims to link lipid composition, nanoparticle morphology, structural integrity, and intracellular transport mechanisms, contributing to the development of next-generation RNA delivery systems with improved efficiency. The project will also strengthen expertise at ICB/NHRF in RNA nanomedicine and cryo-EM-based structural analysis.