The Institute of Chemical Biology (ICB) is the only institute in Greece dedicated to cutting-edge research at the interface of Chemistry and Biology. Through an integrative, interdisciplinary approach, ICB addresses critical challenges in health, drug discovery, and biotechnology.

ICB draws upon and combines the expertise and synergies of its scientific personnel with its state-of-the-art infrastructure, aiming to promote research, education and innovation. ICB by continuously strengthening its uniqueness has succeeded in maximizing its research performance and impact within the national and international research ecosystem.

Strategic research pillars

Drug discovery
I

ICB is unique in Greece in Drug research employing a comprehensive integrated approach encompassing all the stages of Drug discovery (structural biology, design, synthesis, biological evaluation in vitro, ex vivo and in vivo, development of nanocarriers for effective delivery) combined with translational research (collaboration with clinicians, biomarker, big data analysis).


Structural Biology and Molecular Modeling Dr. Evangelia Chrysina, Prof. Panagiotis Kastritis, Dr. Katerina Tsitsanou, Dr. Maria Zervou, Dr. Spyros Zographos, Prof. Panagiotis Zoumpoulakis
Medicinal and Organic Chemistry Dr. Cecile Arbez-Gindre, Dr. Theodora Calogeropoulou, Dr. Christos Chochos, Dr. Vasilis Gregoriou, Dr. Ioannis Kostas, Dr. Maria Koufaki, Dr. George Magoulas , Dr. Kyriakos Prousis
Molecular and cellular biology for basic and translational research Dr. Niki Chondrogianni, Dr. Efstathios Gonos, Dr. Theodora Katsila, Dr. Dimitra Mitsiou, Dr. Alexandros Pintzas, Dr. Vassiliki Pletsa, Dr. Vassilis Souliotis, Dr. Katerina Tsitsanou, Dr. Vassilis Zoumpourlis
Holistic approaches for biomarker discovery Dr. Aristotelis Chatziioannou, Dr. Panagiotis Georgiadis, Dr. Spiros Karakitsios, Dr. Theodora Katsila, Dr. Olga Papadodima, Dr. Alexandros Pintzas, Dr. Vassiliki Pletsa, Dr. Vassilis Souliotis, Dr. Alexandra Voutsina, Dr. Maria Zervou
(Nano)Biotechnology and Synthetic Biology Dr. Christos Chochos, Dr. Vasilis Gregoriou, Dr. Evgenia Mitsou, Dr. Vassiliki Papadimitriou, Dr. Georgios Skretas, Dr. Aristotelis Xenakis, Dr. Maria Zoumpanioti
Holistic approaches in health
II

ICB applies a combination of holistic chemical, biological and computational technologies (genomics, epigenomics, proteomics, transcriptomics and metabolomics) to characterize a wide range of samples, to study the mechanism of disease onset and progression and the efficacy/toxicity of drugs and other therapeutic approaches, and for the discovery of biomarkers related to environmental exposure, population heterogeneity, disease pathogenesis and development of drug resistance.


Holistic approaches for biomarker discovery Dr. Aristotelis Chatziioannou, Dr. Panagiotis Georgiadis, Dr. Spiros Karakitsios, Dr. Theodora Katsila, Dr. Olga Papadodima, Dr. Alexandros Pintzas, Dr. Vassiliki Pletsa, Dr. Vassilis Souliotis, Dr. Alexandra Voutsina, Dr. Maria Zervou
Molecular and cellular biology for basic and translational research Dr. Niki Chondrogianni, Dr. Efstathios Gonos, Dr. Theodora Katsila, Dr. Dimitra Mitsiou, Dr. Alexandros Pintzas, Dr. Vassiliki Pletsa, Dr. Vassilis Souliotis, Dr. Katerina Tsitsanou, Dr. Vassilis Zoumpourlis
Biotechnology
III

ICB applies biotechnological approaches, nanotechnology and green chemistry to produce compounds and nanocarriers with applications in food, pharmaceuticals, cosmetics and chemicals.


(Nano)Biotechnology and Synthetic Biology Dr. Christos Chochos, Dr. Vasilis Gregoriou, Dr. Evgenia Mitsou, Dr. Vassiliki Papadimitriou, Dr. Georgios Skretas, Dr. Aristotelis Xenakis, Dr. Maria Zoumpanioti
Medicinal and Organic Chemistry Dr. Cecile Arbez-Gindre, Dr. Theodora Calogeropoulou, Dr. Christos Chochos, Dr. Vasilis Gregoriou, Dr. Ioannis Kostas, Dr. Maria Koufaki, Dr. George Magoulas , Dr. Kyriakos Prousis

Click on a pillar for more information

Research Infrastructure & Services

ICB has state-of-the-art scientific equipment and is currently considered one of the best equipped research institutes in Greece, particularly in the fields of Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS) and X-ray Protein Crystallography.

ICB together with the TPCI, operate a large set of advanced instrumentation, acquired through funding from the European Union – NextGenerationEU, co-financed by national resources and the European Investment Bank, within the framework of the National Recovery and Resilience Plan “Greece 2.0”.

An integral part of ICB’s activities is the provision of specialized services to research and technology centers, universities, health institutions and industries both in the country and abroad.

ICB researchers, utilizing their expertise and the Institute’s state-of-the-art infrastructure, provide scientific services in selected application areas to academic institutions, health institutions (hospitals) and the private sector (Pharmaceutical Industry, Chemical, Food & Cosmetics Industry).