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CLOSEPostdoctoral Fellowship under the Marie Skłodowska-Curie Actions for the project CryoLipNano awarded to Dr. Panagiota Papadopoulou
Dr Panagiota Papadopoulou has been awarded a Marie Skłodowska-Curie Postdoctoral Fellowship (HORIZON-MSCA-2024-PF-01-01) for the project CryoLipNano, with a total budget of €197,263.68, which will be implemented at the ICB/NHRF.
This project focuses on investigating the ultrastructure and intracellular trafficking of RNA lipid nanoparticles (LNPs) using advanced cryo-electron microscopy, imaging techniques, and proteomics. LNPs currently represent the most advanced and clinically approved platform for RNA delivery, yet only a small fraction successfully releases RNA into the cell cytoplasm.
CryoLipNano aims to link lipid composition, nanoparticle morphology, structural integrity, and intracellular transport mechanisms, contributing to the development of next-generation RNA delivery systems with improved efficiency. The project will also strengthen expertise at ICB/NHRF in RNA nanomedicine and cryo-EM-based structural analysis.