Στερεοεπιλεκτικότητα αντιδράσεων με μέταλλα μετάπτωσης ως καταλύτες

A number of organic reactions catalyzed by transition metal complexes produce products that are richer in a certain stereoisomer, leading to stereoselective procedures. The allylic alkylation catalyzed by Mo complexes was pioneered by Trost at Stanford University in 1998. We performed extended mechanistic studies of these reactions and using highly accurate computations of a great number of transition states, we managed to explain the streoselectivity in the process. Structural effects were explained and the role of hydrogen bonding elucidated.

Key Publications

Inorg. Chim. Acta 489 , 164 (2019)